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Did diabetes treatment do this to him?



 
 
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Old April 19th 08, 02:04 PM posted to rec.pets.cats.health+behav
Phil P.
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Posts: 1,027
Default Did diabetes treatment do this to him?


"Charles Packer" wrote in message
...
On Apr 18, 9:57 am, wrote:
You should never ignore a cat's possible condition just because its
not "fatal" or they are acting normally.


Think about your choice of words here. If I had been
_ignoring_ the cat's condition, it never would have
occurred to me to post a query to this newsgroup,
right?


Actually, it seemed to me like you came here looking for people to support
your position not to treat the cat. I didn't detect any genuine feelings or
concern for the cat- but that's me.


Sloppiness like that has derailed many a discussion
in newsgroups. To get this one back on a useful track,
I'd like to know: Have there been any peer-reviewed
studies of the success rate of the diabetes treatment
advocated in this thread?



What do you consider "success"?

Success is bringing a diabetic cat's blood glucose levels into the normal
range and maintaining it- or driving the cat's diabetes into remission.
Cats whose diabetes is regulated but don't go into remission can still have
a good quality of life for many years. That's success to me.

Here's your study:

J Vet Intern Med. 2006 Mar-Apr;20(2):234-8.

Use of glargine and lente insulins in cats with diabetes mellitus.

Weaver KE, Rozanski EA, Mahony OM, Chan DL, Freeman LM.

Department of Clinical Sciences, Cummings School of Veterinary Medicine,
Tufts
University, North Grafton, MA 01536, USA.

The goals of this study were to compare the efficacy of once-daily
administered
Glargine insulin to twice-daily administered Lente insulin in cats with
diabetes
mellitus and to describe the use of a high-protein, low-carbohydrate diet
designed for the management of diabetes mellitus in cats. All cats with
naturally
occurring diabetes mellitus were eligible for inclusion. Baseline testing
included a physical examination, serum biochemistry, urinalysis and urine
culture, serum thyroxine concentration, and serum fructosamine
concentration. All
cats were fed the high-protein, low-carbohydrate diet exclusively. Cats were
randomized to receive either 0.5 U/kg Lente insulin q12h or 0.5 U/kg
Glargine
insulin q24h. Re-evaluations were performed on all cats at weeks 1, 2, 4, 8,
and
12, and included an assessment of clinical signs, physical examination,
16-hour
blood glucose curve, and serum fructosamine concentrations. Thirteen cats
completed the study (Lente, n = 7, Glargine, n = 6). There was significant
improvement in serum fructosamine and glucose concentrations in all cats but
there was no significant difference between the 2 insulin groups. Four of
the 13
cats were in complete remission by the end of the study period (Lente, n =
3;
Glargine, n = 1). The results of the study support the use of once-daily
insulin
Glargine or twice-daily Lente insulin in combination with a high-protein,
low-carbohydrate diet for treatment of feline diabetes mellitus.


PMID: 16594577 [PubMed - indexed for MEDLINE]




 




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