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Did diabetes treatment do this to him?
"Charles Packer" wrote in message ... On Apr 18, 9:57 am, wrote: You should never ignore a cat's possible condition just because its not "fatal" or they are acting normally. Think about your choice of words here. If I had been _ignoring_ the cat's condition, it never would have occurred to me to post a query to this newsgroup, right? Actually, it seemed to me like you came here looking for people to support your position not to treat the cat. I didn't detect any genuine feelings or concern for the cat- but that's me. Sloppiness like that has derailed many a discussion in newsgroups. To get this one back on a useful track, I'd like to know: Have there been any peer-reviewed studies of the success rate of the diabetes treatment advocated in this thread? What do you consider "success"? Success is bringing a diabetic cat's blood glucose levels into the normal range and maintaining it- or driving the cat's diabetes into remission. Cats whose diabetes is regulated but don't go into remission can still have a good quality of life for many years. That's success to me. Here's your study: J Vet Intern Med. 2006 Mar-Apr;20(2):234-8. Use of glargine and lente insulins in cats with diabetes mellitus. Weaver KE, Rozanski EA, Mahony OM, Chan DL, Freeman LM. Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA. The goals of this study were to compare the efficacy of once-daily administered Glargine insulin to twice-daily administered Lente insulin in cats with diabetes mellitus and to describe the use of a high-protein, low-carbohydrate diet designed for the management of diabetes mellitus in cats. All cats with naturally occurring diabetes mellitus were eligible for inclusion. Baseline testing included a physical examination, serum biochemistry, urinalysis and urine culture, serum thyroxine concentration, and serum fructosamine concentration. All cats were fed the high-protein, low-carbohydrate diet exclusively. Cats were randomized to receive either 0.5 U/kg Lente insulin q12h or 0.5 U/kg Glargine insulin q24h. Re-evaluations were performed on all cats at weeks 1, 2, 4, 8, and 12, and included an assessment of clinical signs, physical examination, 16-hour blood glucose curve, and serum fructosamine concentrations. Thirteen cats completed the study (Lente, n = 7, Glargine, n = 6). There was significant improvement in serum fructosamine and glucose concentrations in all cats but there was no significant difference between the 2 insulin groups. Four of the 13 cats were in complete remission by the end of the study period (Lente, n = 3; Glargine, n = 1). The results of the study support the use of once-daily insulin Glargine or twice-daily Lente insulin in combination with a high-protein, low-carbohydrate diet for treatment of feline diabetes mellitus. PMID: 16594577 [PubMed - indexed for MEDLINE] |
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